UPDATED EFFICACY OF CT103A, FULLY HUMAN BCMA-DIRECTED CAR-T CELLS, IN RELAPSED/REFRACTORY MULTIPLE MYELOMA

Presentation during EHA2022: All Oral presentations were presented between Friday, June 10 and Sunday, June 12 and is accessible for on-demand viewing from Monday, June 20 until Monday, August 15, 2022 on the Congress platform. CT103A, a fully human BCMA-directed CAR-T therapy, showed excellent safety and promising efficacy in the ongoing phase 1/2 FUMANBA-1 study (ChiCTR1800018137, […]

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A Promising CAR-T For T Cell Blood Cancer Reported Duing EHA 2022

During The European Hematology Association (EHA), Dr. Peggy Lu from Lu Daopei Hospital gave a oral speech concerning CAR-T therapy based on CD7 for relapsed & refractory T cell hematologic malignancies. T cell malignant tumor is a kind of hematological tumor with high recurrence rate and mortality. The co expression of CD7 by CAR-T cells and malignant […]

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Legend Biotech Announces U.S. FDA Clearance of IND Application for Solid Tumor CAR-T, LB1908 for Relapsed or Refractory Gastric, Esophageal and Pancreatic Cancers

Legend Biotech Corporation (NASDAQ: LEGN) (Legend Biotech), a global biotechnology company developing, manufacturing and commercializing novel therapies to treat life-threatening diseases, ON June 3, 2022 announced that the U.S. Food and Drug Administration (FDA) has cleared its investigational new drug (IND) application to evaluate LB1908 in a Phase 1 clinical trial in the United States. […]

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Innovent and IASO Bio Jointly Announce the NMPA Acceptance of the New Drug Application for Equecabtagene Autoleucel for the Treatment of Relapsed and/or Refractory Multiple Myeloma

SAN FRANCISCO and SUZHOU, China, June 6, 2022  /PRNewswire/ — Innovent Biologics, Inc. (“Innovent”) (HKEX: 01801), a world-class biopharmaceutical company that develops, manufactures and commercializes high-quality medicines for the treatment of oncology, autoimmune, metabolic, ophthalmology and other major diseases, and IASO Biotherapeutics (“IASO Bio”), a clinical-stage biopharmaceutical company engaged in discovering, developing, and manufacturing innovative cell therapies and […]

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Yescarta® Receives U.S. FDA Approval as First CAR T Cell Therapy for Initial Treatment of Relapsed or Refractory Large B-cell Lymphoma (LBCL)

SANTA MONICA, Calif.–(BUSINESS WIRE)–Kite, a Gilead Company (Nasdaq: GILD), today announced the U.S. Food and Drug Administration (FDA) has approved Yescarta® (axicabtagene ciloleucel) CAR T-cell therapy for adult patients with large B-cell lymphoma that is refractory to first-line chemoimmunotherapy or that relapses within 12 months of first-line chemoimmunotherapy. Yescarta demonstrated a clinically meaningful and statistically significant […]

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A Domestic Patient With Multiple Myeloma But No BCMA Expression Are In Good Condition After Treatment

A female patient from China was diagnosed as “multiple myeloma IgD-λ type III A” in 2018. The patient received a first-line treatment regimen based on bortezomib, and the efficacy evaluation was CR after 3 cycles. In October 2018 Monthly autologous hematopoietic stem cell transplantation was performed as consolidation therapy, followed by oral lenalidomide maintenance therapy. […]

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FDA Fast Track Designation for its First Solid Tumor Candidate, ALLO-316 in the Treatment of Renal Cell Carcinoma

SOUTH SAN FRANCISCO, Calif., March 10, 2022 (GLOBE NEWSWIRE) — Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T™) products for cancer, today announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation (FTD) to ALLO-316, the Company’s first AlloCAR T solid tumor clinical candidate for the treatment […]

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Focus on universal CAR-NK cell therapy! Medicilon’s partner iMBioRay completes 230 million Series A financing

Accelerating the Advancement of Universal CAR-NK Cell Therapy Founded in 2014, iMBioRay is engaged in the treatment of tumors and immune diseases. In 2016, it focused on the development of innovative general-purpose off-the-shelf CAR-NK cell therapy. Through its original technology platform, it has developed a series of cell and antibody drugs, committed to In order to […]

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